Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Hypocalcaemia and calcium deficiency states 0.5-4 g/day in 1-3 divided doses. Hyperacidity 0.5-3 g as symptoms occur. Max: 7.5 g/day for up to 2 weeks. Hyperphosphataemia in patients with chronic renal failure 3-7 g/day in divided doses; adjust according to patient’s serum phosphate level.
Dosage Details
Oral
Hyperphosphataemia in patients with chronic renal failure
Adult: 3-7 g daily in divided doses. Adjust according to patient’s serum phosphate level.
Oral
Hyperacidity
Adult: 0.5-3 g as symptoms occur. Max: 7.5 g daily for up to 2 weeks. Dosage may vary according to product being used.
Child: 2-5 years 0.375-0.4 g as symptoms occur. Max: 1.5 g daily for up to 2 weeks; 6-11 years 0.75-0.8 g as symptoms occur. Max: 3 g daily for up to 2 weeks; ≥12 years Same as adult dose. Dosage may vary according to product being used.
Oral
Hypocalcaemia and calcium deficiency states
Adult: 0.5-4 g daily in 1-3 divided doses. Dosage may vary according to product being used.
Child: 6-10 years 500 mg daily; >10 years 1 g daily. Dosage may vary according to product being used.
Renal Impairment
CrCl (mL/min) Dosage
<25/min Dosage adjustment may be needed based on serum Ca levels.
Administration
May be taken with or without food. Take w/ meals for better absorption. Avoid taking w/ large amount of fibre-rich food.
Contraindications
Patients with hypercalcaemia resulting from myeloma, bone metastases, or other malignant bone disease, sarcoidosis, primary hyperparathyroidism, vitamin D overdosage, long term immobilisation accompanied by hypercalcaemia and/or hypercalciuria; severe hypercalciuria, calci-lithiasis, and renal calculi. Severe renal failure untreated by renal dialysis.
Special Precautions
Patients with achlorhydria, hypoparathyroid disease, history of nephrolithiasis, mild hypercalciuria. Mild to moderate renal impairment. Pregnancy and lactation.
Adverse Reactions
Significant: Constipation, flatulence.
Endocrine disorders: Hypercalcaemia, hypophosphataemia, milk-alkali syndrome.
Gastrointestinal disorders: Abdominal pain, diarrhoea, hyperacidity (acid rebound), nausea, vomiting, xerostomia.
Metabolism and nutrition disorders: Anorexia.
Nervous system disorders: Headache.
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Hypocalcaemia and calcium deficiency states 0.5-4 g/day in 1-3 divided doses. Hyperacidity 0.5-3 g as symptoms occur. Max: 7.5 g/day for up to 2 weeks. Hyperphosphataemia in patients with chronic renal failure 3-7 g/day in divided doses; adjust according to patient’s serum phosphate level.
Dosage Details
Oral
Hyperphosphataemia in patients with chronic renal failure
Adult: 3-7 g daily in divided doses. Adjust according to patient’s serum phosphate level.
Oral
Hyperacidity
Adult: 0.5-3 g as symptoms occur. Max: 7.5 g daily for up to 2 weeks. Dosage may vary according to product being used.
Child: 2-5 years 0.375-0.4 g as symptoms occur. Max: 1.5 g daily for up to 2 weeks; 6-11 years 0.75-0.8 g as symptoms occur. Max: 3 g daily for up to 2 weeks; ≥12 years Same as adult dose. Dosage may vary according to product being used.
Oral
Hypocalcaemia and calcium deficiency states
Adult: 0.5-4 g daily in 1-3 divided doses. Dosage may vary according to product being used.
Child: 6-10 years 500 mg daily; >10 years 1 g daily. Dosage may vary according to product being used.
Renal Impairment
CrCl (mL/min) Dosage
<25/min Dosage adjustment may be needed based on serum Ca levels.
Administration
May be taken with or without food. Take w/ meals for better absorption. Avoid taking w/ large amount of fibre-rich food.
Contraindications
Patients with hypercalcaemia resulting from myeloma, bone metastases, or other malignant bone disease, sarcoidosis, primary hyperparathyroidism, vitamin D overdosage, long term immobilisation accompanied by hypercalcaemia and/or hypercalciuria; severe hypercalciuria, calci-lithiasis, and renal calculi. Severe renal failure untreated by renal dialysis.
Special Precautions
Patients with achlorhydria, hypoparathyroid disease, history of nephrolithiasis, mild hypercalciuria. Mild to moderate renal impairment. Pregnancy and lactation.
Adverse Reactions
Significant: Constipation, flatulence.
Endocrine disorders: Hypercalcaemia, hypophosphataemia, milk-alkali syndrome.
Gastrointestinal disorders: Abdominal pain, diarrhoea, hyperacidity (acid rebound), nausea, vomiting, xerostomia.
Metabolism and nutrition disorders: Anorexia.
Nervous system disorders: Headache.