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NEUROBION 10'S VITAMIN (B1,B6,B12)


    RM 8.00

TAB

Contents
Vitamin B-complex.

Indications/Uses
Film-Coated Tablet: Neurological and other disorders associated with disturbance of metabolic functions influenced by B-complex vitamins, including diabetic polyneuropathy, alcoholic peripheral neuritis and post-influenza neuropathies.
Treatment of neuritis and neuralgia of the spinal nerves, especially facial paresis, cervical syndrome, low back pain, and ischialgia.

Dosage/Direction for Use
Film-Coated Tablet: 1 tab 3 times daily to treat moderate cases, or to provide interval and follow-up therapy for a course of injections unless prescribed otherwise by physician.
The dosage and duration of the treatment is determined by the physician depending on the condition of the patient.
Administration: Neurobion tab are swallowed without chewing with a little liquid with or after meals.

Overdosage
Sensorial neuropathy and other sensorial neuropathy syndromes which can be caused by long-term administration of high doses of pyridoxine improve gradually upon vitamin discontinuation.

Contraindications
Hypersensitivity to any of the active ingredients or excipients of Neurobion (see Description).
Use in children: Neurobion film-coated tablets are not suitable for the treatment of children below the age of 14 years due to the high content of active ingredients.

Special Precautions
Neuropathies are described under long-term intake (6-12 months) of >50 mg mean daily dose of vitamin B6. Therefore, under long-term treatment, regular monitoring is recommended.
Neurobion film-coated tablets contain sucrose; therefore, its use is not recommended in patients with intolerance to some sugars (ie, rare hereditary galactose or fructose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency, or sucrose-isomaltase insufficiency).
Use in pregnancy & lactation: No risks have become known associated with the use of Neurobion during pregnancy at the recommended dosage.
Vitamins B1, B6 and B12 are secreted into human breast milk, but risks of overdosage for the infant are not known. In individual cases, high doses of vitamin B6 ie, >600 mg daily, may inhibit the production of breast milk.

Use In Pregnancy & Lactation
No risks have become known associated with the use of Neurobion during pregnancy at the recommended dosage.
Vitamins B1, B6 and B12 are secreted into human breast milk, but risks of overdosage for the infant are not known. In individual cases, high doses of vitamin B6 ie, >600 mg daily, may inhibit the production of breast milk.

Adverse Reactions
Hypersensitivity reactions to vitamin B1 eg, sweating, tachycardia (rapid heart beat), and skin reactions with itching and urticaria are very rare.
Chromaturia ("reddish urine", appears during the first 8 hours after an administration and typically resolves within 8 hours after an administration and typically resolves within 48 hours) may occur.
Gastrointestinal complaints eg, nausea, vomiting, diarrhoea or abdominal pain may occur.

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