Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Constipation 5-10 mg daily before bedtime. Max: 20 mg. Bowel evacuation For preparation of diagnostic procedures and in pre- and postoperative treatment: 10 mg in the morning and evening, followed by 10 mg rectal supp/enema on the following morning. Rectal Constipation As supp or enema: 10 mg daily.
Administration
Should be taken on an empty stomach. Do not take w/in 1 hr of antacids, milk or other dairy products.
Contraindications
Severe dehydration, ileus, intestinal obstruction, acute abdominal conditions (e.g. appendicitis, acute inflammatory bowel disease, severe abdominal pain). Rectal: Anal fissures, proctitis or ulcerated haemorrhoids.
Special Precautions
Patient with inflammatory bowel disease. Renal impairment. Children. Pregnancy and lactation. Avoid prolonged use (>5 days).
Adverse Reactions
Significant: Fluid and electrolyte imbalance e.g. metabolic acidosis or alkalosis, hypocalcaemia, hypokalaemia (prolonged use).
Gastrointestinal disorders: Abdominal pain, bloody diarrhoea, nausea, abdominal cramps, haematochezia, vomiting, abdominal discomfort, anorectal discomfort, rectal burning (suppository). Rarely, colitis.
Metabolism and nutrition disorders: Rarely, dehydration.
Nervous system disorders: Dizziness.
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Constipation 5-10 mg daily before bedtime. Max: 20 mg. Bowel evacuation For preparation of diagnostic procedures and in pre- and postoperative treatment: 10 mg in the morning and evening, followed by 10 mg rectal supp/enema on the following morning. Rectal Constipation As supp or enema: 10 mg daily.
Administration
Should be taken on an empty stomach. Do not take w/in 1 hr of antacids, milk or other dairy products.
Contraindications
Severe dehydration, ileus, intestinal obstruction, acute abdominal conditions (e.g. appendicitis, acute inflammatory bowel disease, severe abdominal pain). Rectal: Anal fissures, proctitis or ulcerated haemorrhoids.
Special Precautions
Patient with inflammatory bowel disease. Renal impairment. Children. Pregnancy and lactation. Avoid prolonged use (>5 days).
Adverse Reactions
Significant: Fluid and electrolyte imbalance e.g. metabolic acidosis or alkalosis, hypocalcaemia, hypokalaemia (prolonged use).
Gastrointestinal disorders: Abdominal pain, bloody diarrhoea, nausea, abdominal cramps, haematochezia, vomiting, abdominal discomfort, anorectal discomfort, rectal burning (suppository). Rarely, colitis.
Metabolism and nutrition disorders: Rarely, dehydration.
Nervous system disorders: Dizziness.